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Klotho Gene Delivery Suppresses Nox2 Expression and Attenuates Oxidative Stress in Rat Aortic Smooth Muscle Cells via the cAMP-PKA Pathway
BACKGROUND AND HYPOTHESIS: Klotho is a recently discovered anti-aging gene. The purpose of this study was to investigate if klotho gene transfer attenuates superoxide production and oxidative stress in rat aorta smooth muscle (RASM) cells. METHODS AND RESULTS: RASM cells were transfected with AAV pl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342395/ https://ncbi.nlm.nih.gov/pubmed/22260450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00796.x |
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