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Haplodeficiency of Klotho Gene Causes Arterial Stiffening via Upregulation of Scleraxis Expression and Induction of Autophagy
The prevalence of arterial stiffness increases with age while the level of the aging-suppressor protein klotho decreases with age. The objective of this study is to assess if haplodeficiency of klotho gene causes arterial stiffness and investigate the underlying mechanism. Pulse wave velocity, a dir...
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| Publicado no: | Hypertension |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600046/ https://ncbi.nlm.nih.gov/pubmed/26324504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06033 |
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