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Autophagy Plays a Critical Role in Klotho Gene Deficiency-induced Arterial Stiffening and Hypertension
OBJECTIVE: Klotho is an anti-aging gene that shortens lifespan when disrupted and extends lifespan when overexpressed. This study investigated whether autophagy plays a role in Klotho gene deficiency-induced arterial stiffening and hypertension. METHODS: Klotho mutant heterozygous (KL+/−) mice and a...
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| Publicado en: | J Mol Med (Berl) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7055468/ https://ncbi.nlm.nih.gov/pubmed/31630227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-019-01841-6 |
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