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Activation of SIRT1 Attenuates Klotho Deficiency-induced Arterial Stiffness and Hypertension by Enhancing AMPKα Activity

Arterial stiffness is an independent risk factor for stroke and myocardial infarction. This study was designed to investigate the role of SIRT1, an important deacetylase, and its relationship with Klotho, a kidney-derived aging-suppressor protein, in the pathogenesis of arterial stiffness and hypert...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hypertension
Prif Awduron: Gao, Diansa, Zuo, Zhong, Tian, Jing, Ali, Quaisar, Lin, Yi, Lei, Han, Sun, Zhongjie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063709/
https://ncbi.nlm.nih.gov/pubmed/27620389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07709
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