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Anti-aging Gene Klotho Deficiency Promoted High Fat Diet-induced Arterial Stiffening via Inactivation of AMP-activated Protein Kinase
Klotho was originally discovered as an aging-suppressor gene. The objective of this study is to investigate if klotho gene deficiency affects high fat diet-induced arterial stiffening. Heterozygous Klotho deficient (KL(+/−)) mice and WT littermates were fed on high fat diet (HFD) or normal diet (ND)...
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| Publicado no: | Hypertension |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752379/ https://ncbi.nlm.nih.gov/pubmed/26781278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06825 |
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