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Anti-aging Gene Klotho Deficiency Promoted High Fat Diet-induced Arterial Stiffening via Inactivation of AMP-activated Protein Kinase
Klotho was originally discovered as an aging-suppressor gene. The objective of this study is to investigate if klotho gene deficiency affects high fat diet-induced arterial stiffening. Heterozygous Klotho deficient (KL(+/−)) mice and WT littermates were fed on high fat diet (HFD) or normal diet (ND)...
Gorde:
| Argitaratua izan da: | Hypertension |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752379/ https://ncbi.nlm.nih.gov/pubmed/26781278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06825 |
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