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Deficiency in AMP-Activated Protein Kinase Exaggerates High Fat Diet-Induced Cardiac Hypertrophy and Contractile Dysfunction
AMPK, a metabolic sensor, protects against ischemic injury and cardiac hypertrophy although its role in obesity is unclear. This study was designed to examine the impact of AMPK deficiency on cardiac dysfunction following high fat feeding. Adult WT and transgenic mice overexpressing a kinase dead (K...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049828/ https://ncbi.nlm.nih.gov/pubmed/21167835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.12.007 |
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