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Tauroursodeoxycholic Acid Mitigates High Fat Diet-Induced Cardiomyocyte Contractile and Intracellular Ca(2+) Anomalies

OBJECTIVES: The endoplasmic reticulum (ER) chaperone tauroursodeoxycholic acid (TUDCA) has exhibited promises in the treatment of obesity, although its impact on obesity-induced cardiac dysfunction is unknown. This study examined the effect of TUDCA on cardiomyocyte function in high-fat diet-induced...

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Autors principals: Turdi, Subat, Hu, Nan, Ren, Jun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647067/
https://ncbi.nlm.nih.gov/pubmed/23667647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063615
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