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AMP-Activated Protein Kinase Deficiency Exacerbates Aging-Induced Myocardial Contractile Dysfunction

Aging is associated with myocardial dysfunction although the underlying mechanism is unclear. AMPK, a key cellular fuel sensor for energy metabolism, is compromised with aging. This study examined the role of AMPK deficiency in aging-associated myocardial dysfunction. Young or old minwild-type (WT)...

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Detalhes bibliográficos
Main Authors: Turdi, Subat, Fan, Xiujuan, Li, Ji, Zhao, Junxing, Huff, Anna F., Du, Min, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910211/
https://ncbi.nlm.nih.gov/pubmed/20477759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00586.x
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