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Arterial Wall Stiffening in Caveolin-1 Deficiency-Induced Pulmonary Artery Hypertension in Mice

BACKGROUND: Pulmonary artery hypertension (PAH) is a complex disorder that can lead to right heart failure. The generation of caveolin-1 deficient mice (CAV-1(−/−)) has provided an alternative genetic model to study the mechanisms of pulmonary hypertension. However, the vascular adaptations in these...

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Pubblicato in:Exp Mech
Autori principali: Moreno, J., Escobedo, D., Calhoun, C., Le Saux, C. Jourdan, Han, H. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993546/
https://ncbi.nlm.nih.gov/pubmed/33776068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11340-020-00666-6
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