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The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension

Hypoxic pulmonary hypertension (HPH) causes extralobar pulmonary artery (PA) stiffening, which potentially impairs right ventricular systolic function. Changes in the extracellular matrix proteins collagen and elastin have been suggested to contribute to this arterial stiffening. We hypothesized tha...

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Detalhes bibliográficos
Main Authors: Ooi, Chen Yen, Wang, Zhijie, Tabima, Diana M., Eickhoff, Jens C., Chesler, Naomi C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006281/
https://ncbi.nlm.nih.gov/pubmed/20852040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00493.2009
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