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The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension

Hypoxic pulmonary hypertension (HPH) causes extralobar pulmonary artery (PA) stiffening, which potentially impairs right ventricular systolic function. Changes in the extracellular matrix proteins collagen and elastin have been suggested to contribute to this arterial stiffening. We hypothesized tha...

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Autors principals: Ooi, Chen Yen, Wang, Zhijie, Tabima, Diana M., Eickhoff, Jens C., Chesler, Naomi C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006281/
https://ncbi.nlm.nih.gov/pubmed/20852040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00493.2009
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