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Role of collagen content and cross-linking in large pulmonary arterial stiffening after chronic hypoxia

Chronic hypoxic pulmonary hypertension (HPH) is associated with large pulmonary artery (PA) stiffening, which is correlated with collagen accumulation. However, the mechanisms by which collagen contributes to PA stiffening remain largely unexplored. Moreover, HPH may alter mechanical properties othe...

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Detalhes bibliográficos
Main Authors: Wang, Zhijie, Chesler, Naomi C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248635/
https://ncbi.nlm.nih.gov/pubmed/21538012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-011-0309-z
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