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Role of collagen content and cross-linking in large pulmonary arterial stiffening after chronic hypoxia

Chronic hypoxic pulmonary hypertension (HPH) is associated with large pulmonary artery (PA) stiffening, which is correlated with collagen accumulation. However, the mechanisms by which collagen contributes to PA stiffening remain largely unexplored. Moreover, HPH may alter mechanical properties othe...

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Detalles Bibliográficos
Main Authors: Wang, Zhijie, Chesler, Naomi C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248635/
https://ncbi.nlm.nih.gov/pubmed/21538012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-011-0309-z
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