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Synonymous but not Silent: The Codon Usage Code for Gene Expression and Protein Folding

Codon usage bias, the preference for certain synonymous codons, is found in all genomes. Although synonymous mutations were previously thought to be silent, a large body of evidence has demonstrated that codon usage can play major roles in determining gene expression levels and protein structures. C...

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Bibliographische Detailangaben
Veröffentlicht in:Annu Rev Biochem
Hauptverfasser: Liu, Yi, Yang, Qian, Zhao, Fangzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284178/
https://ncbi.nlm.nih.gov/pubmed/33441035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-071320-112701
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