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Synonymous but not Silent: The Codon Usage Code for Gene Expression and Protein Folding

Codon usage bias, the preference for certain synonymous codons, is found in all genomes. Although synonymous mutations were previously thought to be silent, a large body of evidence has demonstrated that codon usage can play major roles in determining gene expression levels and protein structures. C...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Annu Rev Biochem
Main Authors: Liu, Yi, Yang, Qian, Zhao, Fangzhou
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284178/
https://ncbi.nlm.nih.gov/pubmed/33441035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-071320-112701
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