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Synonymous but not Silent: The Codon Usage Code for Gene Expression and Protein Folding

Codon usage bias, the preference for certain synonymous codons, is found in all genomes. Although synonymous mutations were previously thought to be silent, a large body of evidence has demonstrated that codon usage can play major roles in determining gene expression levels and protein structures. C...

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Bibliografische gegevens
Gepubliceerd in:Annu Rev Biochem
Hoofdauteurs: Liu, Yi, Yang, Qian, Zhao, Fangzhou
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284178/
https://ncbi.nlm.nih.gov/pubmed/33441035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-071320-112701
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