Effects of codon usage on gene expression are promoter context dependent

Codon usage bias is a universal feature of all genomes. Although codon usage has been shown to regulate mRNA and protein levels by influencing mRNA decay and transcription in eukaryotes, little or no genome-wide correlations between codon usage and mRNA levels are detected in mammalian cells, raisin...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Yang, Qian, Lyu, Xueliang, Zhao, Fangzhou, Liu, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826287/
https://ncbi.nlm.nih.gov/pubmed/33410890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1253
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