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Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression

Genome-wide distribution of histone H3K18 and H3K27 acetyltransferases, CBP (CREBBP) and p300 (EP300), is used to map enhancers and promoters, but whether these elements functionally require CBP/p300 remains largely uncertain. Here we compared global CBP recruitment with gene expression in wild-type...

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Detalhes bibliográficos
Main Authors: Kasper, Lawryn H., Qu, Chunxu, Obenauer, John C., McGoldrick, Daniel J., Brindle, Paul K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191404/
https://ncbi.nlm.nih.gov/pubmed/25249627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku827
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