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Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes

Signal Transducers and Activators of Transcription (STAT) 5A/B regulate cytokine-inducible genes upon binding to GAS motifs. It is not known what percentage of genes with GAS motifs bind to and are regulated by STAT5. Moreover, it is not clear whether genome-wide STAT5 binding is modulated by its co...

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Detalhes bibliográficos
Main Authors: Zhu, Bing-Mei, Kang, Keunsoo, Yu, Ji Hoon, Chen, Weiping, Smith, Harold E., Lee, Daeyoup, Sun, Hong-Wei, Wei, Lai, Hennighausen, Lothar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378893/
https://ncbi.nlm.nih.gov/pubmed/22319210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks056
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