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Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes

Establishment and differentiation of mammary alveoli during pregnancy are controlled by prolactin through the transcription factors STAT5A and STAT5B (STAT5), which also regulate temporal activation of mammary signature genes. This study addressed the question whether the methyltransferase and trans...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Yoo, Kyung Hyun, Oh, Sumin, Kang, Keunsoo, Hensel, Tim, Robinson, Gertraud W., Hennighausen, Lothar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605299/
https://ncbi.nlm.nih.gov/pubmed/26250110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv776
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