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Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes

Establishment and differentiation of mammary alveoli during pregnancy are controlled by prolactin through the transcription factors STAT5A and STAT5B (STAT5), which also regulate temporal activation of mammary signature genes. This study addressed the question whether the methyltransferase and trans...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Yoo, Kyung Hyun, Oh, Sumin, Kang, Keunsoo, Hensel, Tim, Robinson, Gertraud W., Hennighausen, Lothar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605299/
https://ncbi.nlm.nih.gov/pubmed/26250110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv776
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