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The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation

The transcription factor STAT5 mediates prolactin signaling and controls functional development of mammary tissue during pregnancy. This study has identified the miR-193b locus, also encoding miRNAs 365-1 and 6365, as a STAT5 target in mammary epithelium. While the locus was characterized by active...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Yoo, Kyung Hyun, Kang, Keunsoo, Feuermann, Yonatan, Jang, Seung Jin, Robinson, Gertraud W., Hennighausen, Lothar
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252501/
https://ncbi.nlm.nih.gov/pubmed/25236432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.09.012
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