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The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation

The transcription factor STAT5 mediates prolactin signaling and controls functional development of mammary tissue during pregnancy. This study has identified the miR-193b locus, also encoding miRNAs 365-1 and 6365, as a STAT5 target in mammary epithelium. While the locus was characterized by active...

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Bibliografische gegevens
Gepubliceerd in:Dev Biol
Hoofdauteurs: Yoo, Kyung Hyun, Kang, Keunsoo, Feuermann, Yonatan, Jang, Seung Jin, Robinson, Gertraud W., Hennighausen, Lothar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252501/
https://ncbi.nlm.nih.gov/pubmed/25236432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.09.012
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