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Synonymous but not Silent: The Codon Usage Code for Gene Expression and Protein Folding

Codon usage bias, the preference for certain synonymous codons, is found in all genomes. Although synonymous mutations were previously thought to be silent, a large body of evidence has demonstrated that codon usage can play major roles in determining gene expression levels and protein structures. C...

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Bibliographic Details
Published in:Annu Rev Biochem
Main Authors: Liu, Yi, Yang, Qian, Zhao, Fangzhou
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284178/
https://ncbi.nlm.nih.gov/pubmed/33441035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-071320-112701
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