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Codon usage influences the local rate of translation elongation to regulate co-translational protein folding

Codon usage bias is a universal feature of eukaryotic and prokaryotic genomes and has been proposed to regulate translation efficiency, accuracy and protein folding based on the assumption that codon usage affects translation dynamics. The roles of codon usage in translation, however, are not clear...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell
Hoofdauteurs: Yu, Chien-Hung, Dang, Yunkun, Zhou, Zhipeng, Wu, Cheng, Zhao, Fangzhou, Sachs, Matthew S., Liu, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561030/
https://ncbi.nlm.nih.gov/pubmed/26321254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.018
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