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eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons
Codon usage bias is a universal feature of eukaryotic and prokaryotic genomes and plays an important role in regulating gene expression levels. A major role of codon usage is thought to regulate protein expression levels by affecting mRNA translation efficiency, but the underlying mechanism is uncle...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755126/ https://ncbi.nlm.nih.gov/pubmed/31410471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz710 |
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