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Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity

In a cell, the folding of a protein molecule into tertiary structure can begin while it is synthesized by the ribosome. The rate at which individual amino acids are incorporated into the elongating nascent chain has been shown to affect the likelihood that proteins will populate their folded state,...

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Detalhes bibliográficos
Publicado no:J Chem Phys
Main Authors: Caniparoli, Luca, O’Brien, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597233/
https://ncbi.nlm.nih.gov/pubmed/25877595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4916914
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