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Accurate prediction of cellular co-translational folding indicates proteins can switch from post- to co-translational folding
The rates at which domains fold and codons are translated are important factors in determining whether a nascent protein will co-translationally fold and function or misfold and malfunction. Here we develop a chemical kinetic model that calculates a protein domain's co-translational folding cur...
Tallennettuna:
| Julkaisussa: | Nat Commun |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4759629/ https://ncbi.nlm.nih.gov/pubmed/26887592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10341 |
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