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Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli

Of the 20 common amino acids, 18 are encoded by multiple synonymous codons. These synonymous codons are not redundant; in fact, all of codons contribute substantially to protein expression, structure and function. In this study, the codon usage pattern of genes in the E. coli was learned from the se...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tian, Jian, Yan, Yaru, Yue, Qingxia, Liu, Xiaoqing, Chu, Xiaoyu, Wu, Ningfeng, Fan, Yunliu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577221/
https://ncbi.nlm.nih.gov/pubmed/28855614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10546-0
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