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Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
BACKGROUND: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The non-synonymous SNPs (nsSNPs) that lead to amino acid changes in the protein product may account for nearly half of the know...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2216041/ https://ncbi.nlm.nih.gov/pubmed/18005451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-450 |
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