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Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines

BACKGROUND: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The non-synonymous SNPs (nsSNPs) that lead to amino acid changes in the protein product may account for nearly half of the know...

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Autors principals: Tian, Jian, Wu, Ningfeng, Guo, Xuexia, Guo, Jun, Zhang, Juhua, Fan, Yunliu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216041/
https://ncbi.nlm.nih.gov/pubmed/18005451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-450
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