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Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli

Of the 20 common amino acids, 18 are encoded by multiple synonymous codons. These synonymous codons are not redundant; in fact, all of codons contribute substantially to protein expression, structure and function. In this study, the codon usage pattern of genes in the E. coli was learned from the se...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Tian, Jian, Yan, Yaru, Yue, Qingxia, Liu, Xiaoqing, Chu, Xiaoyu, Wu, Ningfeng, Fan, Yunliu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577221/
https://ncbi.nlm.nih.gov/pubmed/28855614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10546-0
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