A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells

Chinese hamster ovary (CHO) cells are widely used for producing biopharmaceuticals, and engineering gene expression in CHO is key to improving drug quality and affordability. However, engineering gene expression or activating silent genes requires accurate annotation of the underlying regulatory ele...

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Veröffentlicht in:NAR Genom Bioinform
Hauptverfasser: Shamie, Isaac, Duttke, Sascha H, Karottki, Karen J la Cour, Han, Claudia Z, Hansen, Anders H, Hefzi, Hooman, Xiong, Kai, Li, Shangzhong, Roth, Samuel J, Tao, Jenhan, Lee, Gyun Min, Glass, Christopher K, Kildegaard, Helene Faustrup, Benner, Christopher, Lewis, Nathan E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276764/
https://ncbi.nlm.nih.gov/pubmed/34268494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab061
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