A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells

Chinese hamster ovary (CHO) cells are widely used for producing biopharmaceuticals, and engineering gene expression in CHO is key to improving drug quality and affordability. However, engineering gene expression or activating silent genes requires accurate annotation of the underlying regulatory ele...

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Dades bibliogràfiques
Publicat a:NAR Genom Bioinform
Autors principals: Shamie, Isaac, Duttke, Sascha H, Karottki, Karen J la Cour, Han, Claudia Z, Hansen, Anders H, Hefzi, Hooman, Xiong, Kai, Li, Shangzhong, Roth, Samuel J, Tao, Jenhan, Lee, Gyun Min, Glass, Christopher K, Kildegaard, Helene Faustrup, Benner, Christopher, Lewis, Nathan E
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Standard Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276764/
https://ncbi.nlm.nih.gov/pubmed/34268494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab061
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