טוען...
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Media and feed optimization have fueled many-fold improvements in mammalian biopharmaceutical production, but genome editing offers an emerging avenue for further enhancing cell metabolism and bioproduction. However, the complexity of metabolism, involving thousands of genes, makes it unclear which...
שמור ב:
| הוצא לאור ב: | Metab Eng |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8193919/ https://ncbi.nlm.nih.gov/pubmed/33813034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2021.03.017 |
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