Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway

Por Lee, Jae Seong, Kallehauge, Thomas Beuchert, Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup
Publicado no Sci Rep (2015)

Multi‐omic profiling ­of EPO‐producing Chinese hamster ovary cell panel reveals metabolic adaptation to heterologous protein production

Por Ley, Daniel, Seresht, Ali Kazemi, Engmark, Mikael, Magdenoska, Olivera, Nielsen, Kristian Fog, Kildegaard, Helene Faustrup, Andersen, Mikael Rørdam
Publicado no Biotechnol Bioeng (2015)

Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data

Por Lund, Anne Mathilde, Kaas, Christian Schrøder, Brandl, Julian, Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup, Kristensen, Claus, Andersen, Mikael Rørdam
Publicado no BMC Syst Biol (2017)

Accelerating Genome Editing in CHO Cells Using CRISPR Cas9 and CRISPy, a Web-Based Target Finding Tool

Por Ronda, Carlotta, Pedersen, Lasse Ebdrup, Hansen, Henning Gram, Kallehauge, Thomas Beuchert, Betenbaugh, Michael J, Nielsen, Alex Toftgaard, Kildegaard, Helene Faustrup
Publicado no Biotechnol Bioeng (2014)

A Versatile System for USER Cloning-Based Assembly of Expression Vectors for Mammalian Cell Engineering

Por Lund, Anne Mathilde, Kildegaard, Helene Faustrup, Petersen, Maja Borup Kjær, Rank, Julie, Hansen, Bjarne Gram, Andersen, Mikael Rørdam, Mortensen, Uffe Hasbro
Publicado em 2014

Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion

Por Kallehauge, Thomas Beuchert, Li, Shangzhong, Pedersen, Lasse Ebdrup, Ha, Tae Kwang, Ley, Daniel, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup, Lee, Gyun Min, Lewis, Nathan E.
Publicado no Sci Rep (2017)

Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells

Por Hansen, Henning Gram, Nilsson, Claes Nymand, Lund, Anne Mathilde, Kol, Stefan, Grav, Lise Marie, Lundqvist, Magnus, Rockberg, Johan, Lee, Gyun Min, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup
Publicado no Sci Rep (2015)