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Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells are widely used as cell factories for the production of biopharmaceuticals. In contrast to the highly optimized production processes for monoclonal antibody (mAb)-based biopharmaceuticals, improving productivity of non-mAb therapeutic glycoproteins is more likely to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hansen, Henning Gram, Nilsson, Claes Nymand, Lund, Anne Mathilde, Kol, Stefan, Grav, Lise Marie, Lundqvist, Magnus, Rockberg, Johan, Lee, Gyun Min, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676018/
https://ncbi.nlm.nih.gov/pubmed/26657798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18016
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