Lanean...
Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay
Loss of the fragile X protein FMRP is a leading cause of intellectual disability and autism(1,2), but the underlying mechanism remains poorly understood. We report that FMRP deficiency results in hyperactivated nonsense-mediated mRNA decay (NMD)(3,4) in human SH-SY5Y neuroblastoma cells and fragile...
Gorde:
| Argitaratua izan da: | Nat Cell Biol |
|---|---|
| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2021
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8273690/ https://ncbi.nlm.nih.gov/pubmed/33420492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-00618-1 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|