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Optimized TrkB Agonist Ameliorates Alzheimer’s Disease Pathologies and Improves Cognitive Functions via Inhibiting Delta-Secretase
[Image: see text] BDNF/TrkB neurotropic pathway, essential for neural synaptic plasticity and survival, is deficient in neurodegenerative diseases including Alzheimer’s disease (AD). Our previous works support that BDNF diminishes AD pathologies by inhibiting delta-secretase, a crucial age-dependent...
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| Wydane w: | ACS Chem Neurosci |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical Society
2021
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8269693/ https://ncbi.nlm.nih.gov/pubmed/34106682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.1c00181 |
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