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Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease with age as a major risk factor. AD is the most common dementia with abnormal structures, including extracellular senile plaques and intraneuronal neurofibrillary tangles, as key neuropathologic hallmarks. The early feature of AD pa...

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Bibliografski detalji
Izdano u:Exp Mol Med
Glavni autori: Kang, Seong Su, Ahn, Eun Hee, Ye, Keqiang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080617/
https://ncbi.nlm.nih.gov/pubmed/32859953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-00494-7
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