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Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disease with age as a major risk factor. AD is the most common dementia with abnormal structures, including extracellular senile plaques and intraneuronal neurofibrillary tangles, as key neuropathologic hallmarks. The early feature of AD pa...
Guardat en:
| Publicat a: | Exp Mol Med |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080617/ https://ncbi.nlm.nih.gov/pubmed/32859953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-00494-7 |
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