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Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disease with age as a major risk factor. AD is the most common dementia with abnormal structures, including extracellular senile plaques and intraneuronal neurofibrillary tangles, as key neuropathologic hallmarks. The early feature of AD pa...
Enregistré dans:
| Publié dans: | Exp Mol Med |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080617/ https://ncbi.nlm.nih.gov/pubmed/32859953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-00494-7 |
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