Nalaganje...
ApoE4 Inhibition of VMAT2 in the Locus Coeruleus Exacerbates Tau Pathology in Alzheimer’s Disease
ApoE4 enhances Tau neurotoxicity and promotes the early onset of AD. Pretangle Tau in the noradrenergic locus coeruleus (LC) is the earliest detectable AD-like pathology in the human brain. However, a direct relationship between ApoE4 and Tau in the LC has not been identified. Here we show that ApoE...
Shranjeno v:
| izdano v: | Acta Neuropathol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8217363/ https://ncbi.nlm.nih.gov/pubmed/33895869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02315-1 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|