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Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus
Degeneration of locus coeruleus (LC) is an underappreciated hallmark of Alzheimer's disease (AD). The LC is the main source of norepinephrine (NE) in the forebrain, and its degeneration is highly correlated with cognitive impairment and amyloid-beta (Aβ) and tangle pathology. Hyperphosphorylate...
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| Publicado no: | Neural Plast |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605916/ https://ncbi.nlm.nih.gov/pubmed/29038736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7829507 |
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