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Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disease with age as a major risk factor. AD is the most common dementia with abnormal structures, including extracellular senile plaques and intraneuronal neurofibrillary tangles, as key neuropathologic hallmarks. The early feature of AD pa...
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| Veröffentlicht in: | Exp Mol Med |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080617/ https://ncbi.nlm.nih.gov/pubmed/32859953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-00494-7 |
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