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Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model

Single-molecule tracking (SMT) allows the study of transcription factor (TF) dynamics in the nucleus, giving important information regarding the diffusion and binding behavior of these proteins in the nuclear environment. Dwell time distributions obtained by SMT for most TFs appear to follow bi-expo...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Garcia, David A, Fettweis, Gregory, Presman, Diego M, Paakinaho, Ville, Jarzynski, Christopher, Upadhyaya, Arpita, Hager, Gordon L
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266587/
https://ncbi.nlm.nih.gov/pubmed/33592625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab072
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