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Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome

Most transcription factors, including nuclear receptors, are widely modeled as binding regulatory elements as monomers, homodimers, or heterodimers. Recent findings in live cells show that the glucocorticoid receptor NR3C1 (also known as GR) forms tetramers on enhancers, owing to an allosteric alter...

詳細記述

保存先:
書誌詳細
出版年:Genome Res
主要な著者: Paakinaho, Ville, Johnson, Thomas A., Presman, Diego M., Hager, Gordon L.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673716/
https://ncbi.nlm.nih.gov/pubmed/31337711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.244814.118
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