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More than meets the dimer: What is the quaternary structure of the glucocorticoid receptor?

It is widely accepted that the glucocorticoid receptor (GR), a ligand-regulated transcription factor that triggers anti-inflammatory responses, binds specific response elements as a homodimer. Here, we will discuss the original primary data that established this model and contrast it with a recent r...

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Hlavní autoři: Presman, Diego M., Hager, Gordon L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279712/
https://ncbi.nlm.nih.gov/pubmed/27764575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1249045
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