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Genome-wide binding potential and regulatory activity of the glucocorticoid receptor’s monomeric and dimeric forms
A widely regarded model for glucocorticoid receptor (GR) action postulates that dimeric binding to DNA regulates unfavorable metabolic pathways while monomeric receptor binding promotes repressive gene responses related to its anti-inflammatory effects. This model has been built upon the characteriz...
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| Gepubliceerd in: | Nat Commun |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8012360/ https://ncbi.nlm.nih.gov/pubmed/33790284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22234-9 |
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