Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model

Single-molecule tracking (SMT) allows the study of transcription factor (TF) dynamics in the nucleus, giving important information regarding the diffusion and binding behavior of these proteins in the nuclear environment. Dwell time distributions obtained by SMT for most TFs appear to follow bi-expo...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Garcia, David A, Fettweis, Gregory, Presman, Diego M, Paakinaho, Ville, Jarzynski, Christopher, Upadhyaya, Arpita, Hager, Gordon L
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
NAR Breakthrough Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266587/
https://ncbi.nlm.nih.gov/pubmed/33592625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab072
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