Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model

Single-molecule tracking (SMT) allows the study of transcription factor (TF) dynamics in the nucleus, giving important information regarding the diffusion and binding behavior of these proteins in the nuclear environment. Dwell time distributions obtained by SMT for most TFs appear to follow bi-expo...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Garcia, David A, Fettweis, Gregory, Presman, Diego M, Paakinaho, Ville, Jarzynski, Christopher, Upadhyaya, Arpita, Hager, Gordon L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
NAR Breakthrough Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266587/
https://ncbi.nlm.nih.gov/pubmed/33592625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab072
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