Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model

Single-molecule tracking (SMT) allows the study of transcription factor (TF) dynamics in the nucleus, giving important information regarding the diffusion and binding behavior of these proteins in the nuclear environment. Dwell time distributions obtained by SMT for most TFs appear to follow bi-expo...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Garcia, David A, Fettweis, Gregory, Presman, Diego M, Paakinaho, Ville, Jarzynski, Christopher, Upadhyaya, Arpita, Hager, Gordon L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
NAR Breakthrough Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266587/
https://ncbi.nlm.nih.gov/pubmed/33592625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab072
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