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Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response

To study how the Zika virus (ZIKV) interacts with the host unfolded protein response (UPR), we undertook a kinetics study. We show that ZIKV infection triggers an atypical tripartite UPR in A549 cells involving transient activation of the effectors X-box-binding protein 1, activating transcription f...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Mufrrih, Mohammed, Chen, Biyao, Chan, Shiu-Wan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265652/
https://ncbi.nlm.nih.gov/pubmed/34106769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00361-21
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