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BiP: Master Regulator of the Unfolded Protein Response and Crucial Factor in Flavivirus Biology


Flaviviruses have an intimate relationship with their host cells, utilizing host proteins during replication. Much of viral genome replication and virion assembly occurs on and within the endoplasmic reticulum (ER). As a cellular protein folding hub, the ER provides an ideal environment for flavivir...

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Foilsithe in:Yale J Biol Med
Main Authors: Lewy, Tyler G., Grabowski, Jeffrey M., Bloom, Marshall E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: YJBM 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482305/
https://ncbi.nlm.nih.gov/pubmed/28656015
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