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Regulated release of ERdj3 from unfolded proteins by BiP
DnaJ proteins often bind to unfolded substrates and recruit their Hsp70 partners. This induces a conformational change in the Hsp70 that stabilizes its binding to substrate. By some unknown mechanism, the DnaJ protein is released. We examined the requirements for the release of ERdj3, a mammalian ER...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580786/ https://ncbi.nlm.nih.gov/pubmed/18923428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.207 |
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