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Regulated release of ERdj3 from unfolded proteins by BiP

DnaJ proteins often bind to unfolded substrates and recruit their Hsp70 partners. This induces a conformational change in the Hsp70 that stabilizes its binding to substrate. By some unknown mechanism, the DnaJ protein is released. We examined the requirements for the release of ERdj3, a mammalian ER...

詳細記述

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書誌詳細
主要な著者: Jin, Yi, Awad, Walid, Petrova, Kseniya, Hendershot, Linda M
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580786/
https://ncbi.nlm.nih.gov/pubmed/18923428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.207
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