Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

GRP78/BiP is a major endoplasmic reticulum (ER) chaperone protein critical for protein quality control of the ER, as well as controlling the activation of the ER-transmembrane signaling molecules. Through creation of mouse models targeting the Grp78 allele, the function of GRP78 in development and d...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Miao, Wey, Shiuan, Zhang, Yi, Ye, Risheng, Lee, Amy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2009
Schlagworte:
Forum Review Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819800/
https://ncbi.nlm.nih.gov/pubmed/19309259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2485
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