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Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders
GRP78/BiP is a major endoplasmic reticulum (ER) chaperone protein critical for protein quality control of the ER, as well as controlling the activation of the ER-transmembrane signaling molecules. Through creation of mouse models targeting the Grp78 allele, the function of GRP78 in development and d...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Mary Ann Liebert, Inc.
2009
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819800/ https://ncbi.nlm.nih.gov/pubmed/19309259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2485 |
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