Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy

Chemotherapy has been reported to upregulate sphingomylinases and increase cellular ceramide, often linked to the induction to cell death. In this work, we show that sublethal doses of doxorubicin and vorinostat still increased cellular ceramide, which was located predominantly at the plasma membran...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FASEB J
Egile Nagusiak: Canals, Daniel, Salamone, Silvia, Santacreu, Bruno Jaime, Nemeth, Erika, Aguilar, Daniel, Hernandez-Corbacho, María José, Adada, Mohamad, Staquicini, Daniela I., Arap, Wadih, Pasqualini, Renata, Haley, John, Obeid, Lina M, Hannun, Yusuf A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265206/
https://ncbi.nlm.nih.gov/pubmed/32307766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000205R
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